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87880
Rapid Group A Streptococcus (Strep A) Antigen Test
Code Description
CPT code 87880 is used to report a rapid antigen test that detects Group A Streptococcus (Strep A) using an immunoassay with direct visual observation. The test is commonly performed on a throat swab to quickly diagnose streptococcal pharyngitis (strep throat) in physician offices, urgent care centers, and other outpatient settings.
When to Use 87880
Common examples include:
Evaluation of sore throat
Suspected streptococcal pharyngitis
Pediatric respiratory illness
Urgent care visits
Primary care office testing
Point-of-care laboratory testing
Rapid diagnosis before antibiotic treatment
Documentation Requirements
Documentation should include:
Medical necessity for testing
Patient signs and symptoms
Ordering provider
Specimen source (throat swab)
Test result
Complete laboratory report
Examples
Example 1
A 10-year-old patient presents with fever, sore throat, and swollen tonsils. The physician performs a rapid Group A Streptococcus antigen test using a throat swab to determine whether antibiotics are indicated. CPT code 87880 is reported.
Example 2
An adult visits an urgent care clinic with painful swallowing and enlarged cervical lymph nodes. A rapid Strep A antigen test is performed during the office visit, making CPT code 87880 the appropriate code.
Common Billing Mistakes
Common billing mistakes include:
Reporting 87880 for molecular (PCR/NAAT) strep testing
Omitting modifier QW when required for CLIA-waived testing
Billing without documented medical necessity
Incorrect specimen documentation
Duplicate laboratory billing
Related CPT Codes
87635
COVID-19 PCR Test
87426
COVID-19 Antigen Test
85025
Complete Blood Count (CBC) With Automated Differential
FAQ
What does CPT code 87880 cover?
CPT code 87880 reports a rapid immunoassay test used to detect Group A Streptococcus antigen from a throat swab.
Is CPT 87880 a rapid strep test?
Yes. It is the CPT code used for a rapid Strep A antigen detection test performed with direct visual observation.
Does CPT 87880 require a throat swab?
Yes. The test is typically performed using a throat swab specimen to detect Group A Streptococcus.
When is CPT 87880 commonly performed?
It is commonly performed in primary care offices, pediatric clinics, urgent care centers, and emergency departments for patients with symptoms of strep throat.






Procedure Type
Microbiology
Test Type
Detection Method
Rapid Strep A Antigen Detection
Immunoassay With Direct Visual Observation


