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87365
COVID-19 Antigen Test
Code Description
CPT code 87635 is used to report a molecular laboratory test that detects SARS-CoV-2 (COVID-19) using nucleic acid amplification technology, such as polymerase chain reaction (PCR). The test identifies viral RNA and is widely used to diagnose active COVID-19 infection due to its high sensitivity and specificity.
When to Use 87635
Common examples include:
Diagnostic COVID-19 PCR testing
Symptomatic patient evaluation
Hospital admission testing
Preoperative COVID-19 screening
Emergency department testing
Public health testing
Confirmatory COVID-19 testing
Documentation Requirements
Documentation should include:
Medical necessity for testing
Ordering provider
Specimen source
Test result
Date of specimen collection
Complete laboratory report
Examples
Example 1
A patient with fever, cough, and shortness of breath undergoes a nasopharyngeal swab for PCR testing to confirm suspected COVID-19 infection. CPT code 87635 is reported.
Example 2
A patient scheduled for elective surgery undergoes preoperative SARS-CoV-2 PCR testing according to hospital protocol. The laboratory performs a nucleic acid amplification test, making CPT code 87635 the appropriate code.
Common Billing Mistakes
Common billing mistakes include:
Reporting 87635 for antigen testing
Selecting the wrong COVID-19 laboratory code
Duplicate laboratory billing
Inadequate documentation
Incorrect diagnosis coding
Related CPT Codes
87426
COVID-19 Antigen Test
85025
Complete Blood Count (CBC) With Automated Differential
85610
Prothrombin Time (PT)
FAQ
What does CPT code 87635 cover?
CPT code 87635 reports a molecular nucleic acid amplification (PCR) test used to detect SARS-CoV-2 (COVID-19).
Is CPT 87635 a PCR test?
Yes. CPT 87635 reports nucleic acid amplification testing, including PCR methods, for detecting SARS-CoV-2.
What is the difference between CPT 87635 and 87426?
CPT 87635 detects viral genetic material using PCR technology, while CPT 87426 detects viral antigens using an immunoassay.
When is CPT 87635 commonly performed?
It is commonly performed for diagnosing active COVID-19 infection, hospital admissions, preoperative screening, public health testing, and confirmatory testing.






Procedure Type
Molecular Pathology
Test Type
Detection Method
COVID-19 PCR Test
Nucleic Acid Amplification (PCR)


