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87426
COVID-19 Antigen Test
Code Description
CPT code 87426 is used to report an immunoassay test that detects the presence of the SARS-CoV-2 (COVID-19) antigen in a patient specimen. The test provides qualitative or semiquantitative results and is commonly used as a rapid diagnostic test for active COVID-19 infection.
When to Use 87426
Common examples include:
Symptomatic COVID-19 testing
Rapid COVID-19 screening
Urgent care testing
Emergency department testing
Occupational health screening
Pre-procedure COVID-19 testing
Point-of-care antigen testing
Documentation Requirements
Documentation should include:
Medical necessity for testing
Ordering provider
Specimen source
Test result
Date of specimen collection
Complete laboratory report
Examples
Example 1
A patient presents to an urgent care clinic with fever, cough, and sore throat. A rapid COVID-19 antigen test is performed using an immunoassay method to evaluate for active SARS-CoV-2 infection. CPT code 87426 is reported.
Example 2
A healthcare worker develops respiratory symptoms after a workplace exposure. A point-of-care COVID-19 antigen test is performed in the office to determine whether the individual has an active infection, making CPT code 87426 the appropriate code.
Common Billing Mistakes
Common billing mistakes include:
Reporting 87426 for molecular (PCR) testing
Billing the wrong COVID-19 laboratory code
Insufficient documentation supporting medical necessity
Incorrect specimen documentation
Duplicate laboratory billing
Related CPT Codes
87635
COVID-19 PCR Test
85025
Complete Blood Count (CBC) With Automated Differential
85610
Prothrombin Time (PT)
FAQ
What does CPT code 87426 cover?
CPT code 87426 reports an immunoassay antigen test used to detect an active SARS-CoV-2 (COVID-19) infection.
Is CPT 87426 a rapid COVID-19 test?
Yes. CPT 87426 is commonly used to report rapid antigen testing performed using immunoassay technology.
What is the difference between CPT 87426 and 87635?
CPT 87426 detects COVID-19 antigens using an immunoassay, while CPT 87635 detects SARS-CoV-2 genetic material using nucleic acid amplification (PCR) technology.
When is CPT 87426 commonly performed?
It is commonly performed in physician offices, urgent care centers, emergency departments, and other healthcare settings for rapid evaluation of active COVID-19 infection.






Procedure Type
Infectious Agent Antigen Detection
Test Type
Detection Method
COVID-19 Antigen Test
Immunoassay


