85025

Complete Blood Count (CBC) With Automated Differential

Code Description

CPT code 85025 is used to report a Complete Blood Count (CBC) with automated white blood cell (WBC) differential. The test measures red blood cells, white blood cells, hemoglobin, hematocrit, platelets, and red blood cell indices while also providing an automated differential count of the various types of white blood cells. It is commonly ordered to evaluate infection, anemia, inflammation, blood disorders, and overall health.

When to Use 85025

Common examples include:

  • Evaluation of infection

  • Anemia workup

  • Routine health screening

  • Monitoring chemotherapy

  • Evaluation of fatigue

  • Investigation of abnormal bleeding

  • Follow-up laboratory testing

Documentation Requirements

Documentation should include:

  • Medical necessity for the laboratory testing

  • Ordering provider

  • Laboratory results

  • Patient diagnosis or symptoms

  • Date of specimen collection

  • Complete laboratory report

Examples
Example 1

A patient presents with fever and fatigue. The physician orders a Complete Blood Count with automated differential to evaluate for infection and other blood abnormalities, making CPT code 85025 the appropriate code.

Example 2

A patient receiving chemotherapy undergoes routine laboratory monitoring before treatment. A CBC with automated white blood cell differential is performed to evaluate blood cell counts and determine whether treatment can safely continue.

Common Billing Mistakes

Common billing mistakes include:

  • Reporting 85025 when a differential was not performed

  • Billing individual CBC components separately

  • Selecting 85027 instead of 85025

  • Insufficient documentation supporting medical necessity

  • Duplicate laboratory billing

Related CPT Codes
85027

Complete Blood Count (CBC)

80048

Basic Metabolic Panel

80053

Comprehensive Metabolic Panel

FAQ

What does CPT code 85025 cover?

CPT code 85025 reports a Complete Blood Count (CBC) that includes an automated white blood cell differential.

What is included in CPT 85025?

The test includes red blood cell count, white blood cell count, hemoglobin, hematocrit, platelet count, red blood cell indices, and an automated white blood cell differential.

What is the difference between CPT 85025 and 85027?

CPT 85025 includes an automated white blood cell differential, while CPT 85027 reports a CBC without a differential.

When is CPT 85025 commonly performed?

It is commonly performed to evaluate infection, anemia, inflammation, blood disorders, chemotherapy patients, and routine health conditions.

Procedure Type

Hematology

Test Type

Includes

Complete Blood Count (CBC)

Automated White Blood Cell Differential