10021

Fine Needle Aspiration Biopsy Without Imaging Guidance

Code Description

CPT code 10021 is used to report a fine needle aspiration (FNA) biopsy performed without imaging guidance. During the procedure, a healthcare provider inserts a thin needle into a lesion, mass, or suspicious area to collect cells for diagnostic examination.

The collected sample is typically sent to a pathology laboratory for evaluation. CPT 10021 is reported only when imaging guidance is not used during the aspiration.

When to Use 10021

Common examples include:

  • palpable thyroid nodules

  • superficial soft tissue masses

  • enlarged lymph nodes

  • breast lesions that can be identified without imaging

Examples
Example 1

A patient presents with a palpable thyroid nodule discovered during a physical examination. The physician performs a fine needle aspiration (FNA) biopsy of the first lesion without imaging guidance in the office to obtain cells for cytologic evaluation. CPT code 10021 is reported.

Example 2

A patient is evaluated for a palpable soft tissue mass in the neck. The physician performs a fine needle aspiration biopsy without ultrasound or other imaging guidance to obtain a tissue sample for diagnosis. The specimen is sent to pathology for cytologic analysis, making CPT code 10021 the appropriate code.

Documentation Requirements

Documentation should include:

  • location of the lesion

  • indication for the biopsy

  • aspiration technique performed

  • specimen collection details

  • patient tolerance of the procedure

Common Billing Mistakes

Common billing mistakes include:

  • reporting 10021 when imaging guidance was used

  • insufficient procedure documentation

  • incorrect lesion identification

  • billing multiple aspiration codes incorrectly

Related CPT Codes
10022

Fine Needle Aspiration Biopsy With Imaging Guidance

11102

Tangential Skin Biopsy

11400

Excision of Benign Lesion

FAQ

What is CPT code 10021?

CPT 10021 describes a fine needle aspiration biopsy performed without imaging guidance.

Does CPT 10021 include ultrasound guidance?

No. If imaging guidance is used, a different CPT code may apply.

What type of specimen is collected?

Cells or fluid are collected through a thin needle for diagnostic evaluation.

Is CPT 10021 considered a biopsy?

Yes. Fine needle aspiration is a biopsy technique used to obtain diagnostic tissue samples.

Procedure Type

Biopsy

Imaging Guidance

MDM Level

Not Included

High