10021
Fine Needle Aspiration Biopsy Without Imaging Guidance
Code Description
CPT code 10021 is used to report a fine needle aspiration (FNA) biopsy performed without imaging guidance. During the procedure, a healthcare provider inserts a thin needle into a lesion, mass, or suspicious area to collect cells for diagnostic examination.
The collected sample is typically sent to a pathology laboratory for evaluation. CPT 10021 is reported only when imaging guidance is not used during the aspiration.
When to Use 10021
Common examples include:
palpable thyroid nodules
superficial soft tissue masses
enlarged lymph nodes
breast lesions that can be identified without imaging
Documentation Requirements
Documentation should include:
location of the lesion
indication for the biopsy
aspiration technique performed
specimen collection details
patient tolerance of the procedure
Common Billing Mistakes
Common billing mistakes include:
reporting 10021 when imaging guidance was used
insufficient procedure documentation
incorrect lesion identification
billing multiple aspiration codes incorrectly
Related CPT Codes
10022- Fine Needle Aspiration Biopsy With Imaging Guidance
11102- Tangential Skin Biopsy
11400- Excision of Benign Lesion
FAQ
What is CPT code 10021?
CPT 10021 describes a fine needle aspiration biopsy performed without imaging guidance.
Does CPT 10021 include ultrasound guidance?
No. If imaging guidance is used, a different CPT code may apply.
What type of specimen is collected?
Cells or fluid are collected through a thin needle for diagnostic evaluation.
Is CPT 10021 considered a biopsy?
Yes. Fine needle aspiration is a biopsy technique used to obtain diagnostic tissue samples.






Procedure Type
Biopsy
Imaging Guidance
MDM Level
Not Included
High


